Can Genotype-Phenotype Correlations Predict Prognosis?
Yes, certain genetic mutations can serve as prognostic markers. For example, mutations in the IDH1 and IDH2 genes in gliomas are associated with a better prognosis compared to gliomas without these mutations. Conversely, mutations in the KRAS gene in colorectal cancer are often associated with a poorer prognosis and resistance to certain therapies.
