What Role Do Genotype-Phenotype Correlations Play in Personalized Medicine?
Genotype-phenotype correlations are pivotal in the era of personalized medicine. By identifying specific genetic mutations, healthcare providers can tailor treatments to the individual patient. For instance, patients with non-small cell lung cancer (NSCLC) who have EGFR mutations may respond well to EGFR inhibitors like gefitinib or erlotinib. Similarly, the presence of HER2 overexpression in breast cancer can guide the use of targeted therapies such as trastuzumab.
