Yes, HPV can be prevented through vaccination. The HPV vaccine is highly effective in preventing infection with the most dangerous types of the virus. It is recommended for preteens (both boys and girls) at age 11 or 12, although it can be given as early as age 9 and up to age 45 in some cases. Other preventive measures include the use of condoms and dental dams during sexual activity, although these methods do not provide complete protection against HPV.