Can Methylation Inhibitors be Used in Cancer Therapy?
Yes, methylation inhibitors, also known as DNA methyltransferase inhibitors (DNMT inhibitors), are being explored as therapeutic agents in cancer treatment. Drugs such as azacitidine and decitabine can reverse aberrant methylation patterns, thereby reactivating silenced tumor suppressor genes. These inhibitors have shown promise in treating certain types of cancers, particularly hematological malignancies.
