Can Targeting Redox Reactions Be a Therapeutic Strategy?
Given the importance of redox balance in cancer, targeting redox reactions has emerged as a potential therapeutic strategy. For instance, drugs that increase ROS production beyond a tolerable threshold can induce cancer cell death. Conversely, inhibiting antioxidant systems in cancer cells can enhance oxidative stress, making them more susceptible to damage. Several clinical trials are exploring redox-targeting agents as part of cancer therapy.
