immune repertoire

Can the Immune Repertoire Be Altered in Cancer Patients?

Yes, cancer and its treatments can significantly alter the immune repertoire. Some cancers can evade immune detection by downregulating antigen presentation or by creating an immunosuppressive environment. Additionally, treatments such as chemotherapy and radiation therapy can deplete immune cells and reduce repertoire diversity. Conversely, immunotherapy aims to enhance the immune repertoire's ability to recognize and attack cancer cells.

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