How Are 2D Monolayer Cultures Used in Drug Testing?
In drug testing, 2D monolayer cultures are used to assess the efficacy and toxicity of potential anti-cancer compounds. Researchers treat cultured cancer cells with different concentrations of drugs and measure outcomes such as cell viability, proliferation, apoptosis, and changes in gene expression. These assays help identify promising candidates for further testing in more complex models and eventually in clinical trials.