In the context of liver cancer, the UCSF Criteria are employed to determine the eligibility of patients for liver transplantation. These criteria are an extension of the Milan Criteria, which initially set the standards for transplant eligibility. For a patient to qualify for a liver transplant under the UCSF Criteria, they must have a single liver tumor no larger than 6.5 cm, or up to three nodules with the largest being no greater than 4.5 cm and the total tumor diameter not exceeding 8 cm. These guidelines ensure that patients selected for transplantation have a high likelihood of benefiting from the procedure with a reduced risk of cancer recurrence.
