How Can CTZ-Related Nausea and Vomiting Be Managed?
Management typically involves the use of antiemetic drugs that target the receptors in the CTZ: - 5-HT3 antagonists: Such as ondansetron and granisetron, block serotonin receptors. - NK1 antagonists: Like aprepitant, block substance P receptors. - D2 antagonists: Including metoclopramide and prochlorperazine, block dopamine receptors. - Cannabinoids: Such as dronabinol, have also been used to manage chemotherapy-induced nausea and vomiting.
