How Can GWAS Findings Be Translated into Clinical Practice?
To translate GWAS findings into clinical practice, several steps are necessary:
Functional Studies: Identified genetic variants need to be studied in the lab to understand their functional impact and role in cancer. Risk Prediction Models: Incorporating multiple genetic variants into risk prediction models can help identify individuals at higher risk for targeted screening and prevention strategies. Drug Development: Understanding the biological pathways affected by genetic variants can lead to the development of new targeted therapies.