Several strategies can enhance the immunogenicity of cancer cells:
Cancer Vaccines: These vaccines aim to stimulate the immune system to recognize and attack cancer cells by introducing tumor antigens. Checkpoint Inhibitors: Drugs like PD-1/PD-L1 inhibitors block proteins that prevent the immune system from attacking cancer cells. Adoptive Cell Transfer: This involves engineering patient-derived T cells to better recognize and attack cancer cells. Oncolytic Viruses: These are designed to selectively infect and kill cancer cells while stimulating an immune response against them.