How Can Researchers Use the Cancer Dependency Map?
Researchers can use the Cancer Dependency Map in several ways:
Target Identification: By identifying genes that are essential for cancer cell survival, researchers can discover new drug targets. Biomarker Discovery: The map can help identify biomarkers that predict which patients are likely to respond to specific therapies. Combination Therapy: Researchers can use the map to identify potential drug combinations that target multiple dependencies, thereby reducing the likelihood of resistance. Mechanistic Insights: The map provides insights into the biological mechanisms underlying cancer cell survival and proliferation, aiding in the understanding of cancer biology.