How Can Targeting Actin Pathways Be a Therapeutic Strategy?
Given the critical role of actin in cancer progression, targeting actin-related pathways presents a potential therapeutic strategy. Inhibitors of actin polymerization, such as cytochalasins, have been studied for their ability to impede cancer cell migration. Additionally, targeting the signaling pathways that regulate actin dynamics, such as those involving Rho GTPases and cofilin, may offer novel approaches to prevent metastasis.
