What Are the Mechanisms of Actin Regulation in Cancer?
Cancer cells exploit several mechanisms to regulate actin dynamics. These include alterations in the expression and activity of actin-binding proteins, such as cofilin, which disassembles actin filaments, and formin, which promotes actin polymerization. Additionally, the Rho family of GTPases is instrumental in actin cytoskeleton reorganization, and their dysregulation is often observed in cancer.
