What Role Does Actin Play in Cell Invasion and Metastasis?
Cell invasion and metastasis require the degradation of the extracellular matrix and the subsequent movement of cancer cells. Actin filaments form structures like lamellipodia and filopodia, which are essential for cell movement and navigation through tissue barriers. Cancer cells manipulate actin dynamics to enhance their invasive capabilities, often through signaling pathways that regulate actin polymerization.