How Can Targeting Fat Metabolism Be a Potential Cancer Therapy?
Given the reliance of cancer cells on lipid metabolism, targeting key enzymes and pathways involved in this process presents a promising therapeutic strategy. Inhibitors of FASN, ACC, and other lipid-metabolizing enzymes have shown potential in preclinical studies by disrupting the energy and biosynthetic supply of cancer cells, thereby inhibiting their growth and survival. Additionally, targeting lipid uptake and storage mechanisms can further starve cancer cells of essential nutrients.
