What Are the Challenges in Targeting Fat Metabolism for Cancer Treatment?
Despite the promise, targeting fat metabolism in cancer therapy faces several challenges. One major issue is the potential for toxicity in normal cells, as lipid metabolism is crucial for overall cellular function. Additionally, cancer cells often exhibit metabolic flexibility, enabling them to switch to alternative energy sources when lipid metabolism is inhibited. Therefore, combinatory approaches targeting multiple metabolic pathways may be necessary to overcome these challenges.
