How Did the Warburg Effect Lead to the Metabolic Theory?
The Warburg Effect, named after Otto Warburg who first described it in the 1920s, is a hallmark of cancer cell metabolism. Warburg observed that cancer cells consumed glucose at a much higher rate than normal cells and produced lactic acid even in oxygen-rich environments. This led to the hypothesis that defective mitochondria were a primary cause of cancer, a key point in the metabolic theory.
