How Do Gene-Gene Interactions Influence Cancer Development?
Cancer is often the result of complex interactions between multiple genes. For instance, mutations in oncogenes and tumor suppressor genes are well-known contributors to cancer. However, the presence of additional genetic variants can influence how these primary mutations affect cellular behavior. For example, a mutation in the TP53 gene, which is crucial for DNA repair, may have different outcomes depending on the status of other genes involved in cell cycle regulation or apoptosis.
