How Do Inherited Genetic Mutations Contribute to Cancer?
Certain inherited genetic mutations can significantly increase the risk of developing cancer. These mutations can affect genes responsible for cell division, DNA repair, and other critical processes. For instance, mutations in the BRCA1 and BRCA2 genes are well-known for increasing the risk of breast and ovarian cancers. Similarly, mutations in the APC gene can lead to familial adenomatous polyposis, a condition that increases the risk of colorectal cancer.