How Do Tumor Microenvironments Influence Immune Evasion?
The tumor microenvironment is a complex network of cells, signaling molecules, and extracellular matrix components that surround and support the tumor. This environment can be immunosuppressive, meaning it actively inhibits the immune response. For example, regulatory T cells (Tregs) and myeloid-derived suppressor cells (MDSCs) within the tumor microenvironment can suppress the activity of cytotoxic T cells and other immune effector cells.
