How Does Aerobic Glycolysis Affect the Tumor Microenvironment?
Aerobic glycolysis significantly impacts the tumor microenvironment. The production of lactate lowers the pH, creating an acidic environment that promotes cancer cell invasion and metastasis. The altered microenvironment also affects immune cell function, contributing to immune escape. Targeting the metabolic interactions within the tumor microenvironment is a promising area of research for developing new anticancer therapies.
