How Does FISH Compare to Other Diagnostic Techniques?
FISH is often compared with other diagnostic techniques such as:
Polymerase Chain Reaction (PCR): While PCR is highly sensitive and can detect small amounts of DNA, FISH provides spatial information about the genetic material within the cell, which PCR cannot. Karyotyping: Karyotyping provides a broad overview of chromosomal abnormalities but lacks the specificity and resolution of FISH. Next-Generation Sequencing (NGS): NGS offers comprehensive genomic information, but FISH is faster and more cost-effective for detecting specific genetic alterations.
