How Does Neuroinflammation Affect Cancer Treatment?
Neuroinflammation can impact the efficacy of cancer treatments in multiple ways. Inflammatory mediators can influence the tumor microenvironment, potentially making cancer cells more resistant to chemotherapy and radiation. For instance, the activation of the NF-kB pathway in response to inflammation can promote cell survival and resistance to apoptosis. Moreover, neuroinflammation can exacerbate treatment-related side effects, such as cognitive impairment and fatigue, thereby affecting the quality of life of cancer patients.
