What Roles do Glial Cells Play in Neuroinflammation and Cancer?
Glial cells, particularly microglia and astrocytes, play critical roles in both neuroinflammation and cancer. Microglia, the primary immune cells of the CNS, can adopt pro-inflammatory (M1) or anti-inflammatory (M2) states. In the tumor microenvironment, they may support tumor growth by promoting angiogenesis and suppressing immune responses. Astrocytes can also contribute to tumor progression by releasing growth factors and cytokines that support cancer cell survival and proliferation.
