How Does Phenotypic Plasticity Affect Cancer Progression?
Phenotypic plasticity is the ability of cancer cells to change their phenotype in response to environmental cues. This plasticity allows cancer cells to adapt to different conditions, such as hypoxia or nutrient deprivation, and to develop resistance to therapies. For instance, epithelial-to-mesenchymal transition (EMT) is a process through which cancer cells acquire a more invasive and metastatic phenotype, contributing to cancer progression and metastasis.
