How Does Structural Biology Contribute to Drug Discovery and Development in Cancer?
Structural biology plays a pivotal role in drug discovery by enabling the rational design of small molecules that can precisely interact with target proteins. The detailed structural information allows researchers to identify active sites and binding pockets on proteins, which can be exploited to design drugs with high specificity and efficacy. This approach has been instrumental in developing targeted therapies that minimize damage to normal cells, reducing side effects compared to conventional chemotherapy.
