How Does the Tumor Microenvironment Influence Non-linearity?
The tumor microenvironment, which includes surrounding blood vessels, immune cells, fibroblasts, and extracellular matrix, plays a crucial role in cancer progression. This environment is highly dynamic and can change in response to the tumor's growth and treatment. These changes can create non-linear effects, where small alterations in the microenvironment can lead to significant shifts in tumor behavior, such as increased invasiveness or resistance to therapy.
