How Has Cryo-EM Contributed to Recent Breakthroughs in Cancer Research?
Cryo-EM has contributed to several groundbreaking discoveries in cancer research. For example, it has been used to determine the structures of key proteins involved in cancer, such as the BRCA1-BRCA2 complex, which plays a critical role in DNA repair. Understanding these structures has provided insights into how mutations in these proteins lead to cancer and how they can be targeted therapeutically.