What Are the Key Applications of Cryo-EM in Cancer Research?
Cryo-EM has several key applications in cancer research:
1. Protein Structure Determination: Cryo-EM enables researchers to determine the structures of cancer-related proteins, such as oncogenes and tumor suppressors, at high resolution. 2. Drug Discovery: By revealing the binding sites of potential drugs on target proteins, Cryo-EM aids in the rational design of new cancer therapies. 3. Mechanistic Studies: Cryo-EM helps elucidate the mechanisms of action for various cancer-related processes, such as DNA repair, signal transduction, and enzyme function. 4. Viral Oncology: It also assists in studying the structure of cancer-causing viruses and their interactions with host cells.
