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How Is Cytotoxicity Measured in Cancer Research?
In cancer research, cytotoxicity is often measured using various assays to determine the effect of a drug on cancer cell viability. Some commonly used assays include:
MTT assay
- Measures cell metabolic activity.
Trypan Blue exclusion
- Determines cell membrane integrity.
Flow cytometry
- Assesses cell cycle and apoptosis.
These assays help researchers evaluate the efficacy and safety of potential cytotoxic agents.
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