How is Resistance to Specific Inhibitors Addressed?
Overcoming resistance involves several strategies:
- Combination Therapies: Using multiple drugs that target different pathways can prevent cancer cells from compensating for the inhibited pathway. - Next-Generation Inhibitors: Developing inhibitors that can bind to multiple sites on a protein or target multiple proteins simultaneously. - Biomarker Identification: Identifying biomarkers that predict resistance can help in tailoring personalized treatment plans.
