Preparing for a 3D mammography exam is similar to preparing for a 2D mammogram. It is advised to schedule the exam for a time when the breasts are least likely to be tender, usually a week after the menstrual period. On the day of the exam, avoid using deodorants, perfumes, or powders, as these can interfere with the images. Wear a two-piece outfit to make it easier to undress from the waist up.