Is P-glycoprotein Expression Uniform in All Cancers?
No, the expression of P-gp varies significantly among different types of cancer. For instance, high levels of P-gp are often found in leukemias, lymphomas, and some solid tumors such as breast cancer and colon cancer. However, not all cancers exhibit high P-gp levels, and its expression can also be influenced by factors such as prior chemotherapy and genetic variations.
