Lamellipodia and filopodia are actin-rich membrane protrusions that are critical for cell movement. Lamellipodia are broad, sheet-like extensions at the leading edge of migrating cells, primarily involved in cell spreading and movement. They are formed by the rapid polymerization of actin filaments, creating a dense network that pushes the membrane forward. On the other hand, filopodia are slender, finger-like projections that extend from the lamellipodia. They are composed of tight bundles of actin filaments and function as sensory structures, probing the environment for chemical and mechanical cues. Together, these structures coordinate to facilitate cell migration.
