Lipases are a diverse group of enzymes that catalyze the breakdown of lipid molecules into free fatty acids and glycerol. These enzymes are not only crucial for normal cellular functions but also in cancer cells, where they facilitate rapid proliferation and migration. In many cancer types, lipases are overexpressed, allowing cancerous cells to sustain their high-energy demands and support biosynthetic processes. This enhanced lipid metabolism is often referred to as the "lipid metabolic reprogramming" of cancer cells.
