What are Organoids and Patient-Derived Xenografts?
Organoids are three-dimensional cell cultures derived from stem cells that can mimic the structure and function of human organs. In the context of cancer research, tumor organoids are developed to replicate the specific properties of a patient's tumor, providing a more physiologically relevant model. Patient-derived xenografts (PDXs) are models where human tumor tissues are implanted into immunocompromised mice. PDXs preserve the architecture and the genetic material of the original tumor, offering another approach to studying cancer in a living organism.
