What Are Potential Therapeutic Targets in Oxidative Biotransformation Pathways?
Therapeutic strategies targeting oxidative biotransformation pathways aim to reduce cancer risk and improve treatment outcomes. Inhibitors of specific CYP enzymes can prevent the activation of procarcinogens. Antioxidants can mitigate oxidative stress, reducing DNA damage and mutagenesis. Additionally, modulating the activity of enzymes involved in biotransformation can enhance the efficacy of chemotherapeutic agents and reduce their toxicity. Research is ongoing to identify novel targets within these pathways for cancer prevention and treatment.
