What are some examples of miRNA sponges used in cancer research?
Several miRNA sponges have been developed and studied in cancer research. For instance, a sponge targeting miR-21, an oncogenic miRNA overexpressed in many cancers, has shown promise in reducing tumor growth in preclinical models. Another example is the sponge targeting miR-155, which has been implicated in various hematologic malignancies. These sponges can help researchers understand the role of specific miRNAs in cancer and potentially lead to novel therapeutic strategies.
