How do miRNA sponges work in the context of cancer?
In cancer, miRNAs play critical roles in regulating genes involved in cell proliferation, apoptosis, and metastasis. miRNA sponges can modulate the expression of these genes by inhibiting oncogenic or tumor-suppressive miRNAs. For example, a miRNA sponge targeting an oncogenic miRNA can restore the function of tumor suppressor genes, potentially inhibiting cancer progression.
