What are Some Key Chromatin Remodeling Genes Involved in Cancer?
Several chromatin remodeling genes have been identified as key players in cancer. These include:
ARID1A: Frequently mutated in ovarian and endometrial cancers. EZH2: Overexpressed in several cancers, including prostate and breast cancer. SMARCA4: Mutated in lung cancer and various other malignancies. ATRX: Associated with pancreatic neuroendocrine tumors and gliomas.