What Are Some Recent Advances in Preclinical Cancer Research?
Recent advances in preclinical research have significantly improved our understanding of cancer and the development of therapies:
1. Organoids and 3D Cultures: These models better mimic the tumor environment compared to traditional 2D cultures, providing more accurate data on drug responses.
2. CRISPR/Cas9 Gene Editing: This technology enables precise modifications of cancer genes, allowing researchers to study their roles and develop targeted therapies.
3. Patient-Derived Xenografts (PDX): These models involve transplanting human tumor tissues into immunodeficient mice, providing a more accurate representation of human cancer biology.
4. High-Throughput Screening: Automation and advanced imaging techniques allow for the rapid screening of thousands of compounds, accelerating the discovery of potential cancer drugs.
