What are the Advantages of FISH in Cancer Research?
FISH offers several advantages in cancer research and diagnosis:
Sensitivity and Specificity: FISH is highly sensitive and specific, making it possible to detect even small genetic changes that other techniques might miss. Visualization: FISH allows for the direct visualization of genetic abnormalities within the context of the cell, providing spatial information that is crucial for understanding the nature of the genetic change. Versatility: FISH can be used on a variety of sample types, including fresh, frozen, and formalin-fixed paraffin-embedded (FFPE) tissues. Quantification: FISH can quantify the number of gene copies, providing important information about gene amplification or deletion.
