What Are the Applications of CRISPR Screening in Cancer?
Identifying Drug Targets: CRISPR screening can uncover genetic vulnerabilities in cancer cells that can be targeted by new or existing drugs, aiding in the development of more effective therapies. Understanding Resistance Mechanisms: By knocking out genes, researchers can identify which genes contribute to drug resistance, allowing for the development of strategies to overcome it. Functional Genomics: Mapping out which genes are essential for cancer cell survival and proliferation provides a deeper understanding of cancer biology.
