What are the challenges in targeting CAMs for cancer therapy?
Despite the potential, there are challenges in targeting CAMs for cancer therapy. One major challenge is the redundancy and compensatory mechanisms among CAMs, which can undermine the efficacy of targeted therapies. Additionally, CAMs are also involved in normal physiological processes, so targeting them could lead to adverse effects. Understanding the context-specific roles of CAMs in different cancer types and stages is crucial for developing effective and safe therapies.
