What are the Challenges of Exome Sequencing in Cancer?
Despite its potential, exome sequencing faces several challenges: - Complexity of Cancer Genomes: Cancer genomes are highly heterogeneous, making it difficult to distinguish between driver and passenger mutations. - Data Interpretation: The vast amount of data generated requires sophisticated bioinformatics tools for analysis and interpretation. - Cost: Although the cost of sequencing has dropped significantly, it still remains a barrier for widespread clinical use. - Ethical and Privacy Concerns: Handling genetic data raises important ethical and privacy issues that need to be addressed.
