What are the Characteristics of Tumor Blood Vessels?
Tumor blood vessels are often characterized by their tortuous and irregular shape. They tend to have a leaky and permeable endothelial lining, which can result in inefficient blood flow and elevated interstitial fluid pressure. This abnormality contributes to a heterogeneous distribution of oxygen and nutrients, leading to regions of hypoxia within the tumor. Hypoxic conditions can further stimulate angiogenesis and promote a more aggressive tumor phenotype.
