Why is Tumor Vasculature Important for Cancer Progression?
The vasculature is crucial for tumor progression because it provides a route for the delivery of nutrients and oxygen which are essential for tumor growth. Additionally, the blood vessels serve as pathways for tumor cells to enter the bloodstream and metastasize to distant organs. The abnormal and leaky nature of tumor blood vessels also makes it challenging for therapeutic agents to penetrate the tumor effectively, impacting the efficacy of treatments like chemotherapy.
