What Are the Clinical Implications of Thymidylate Synthase in Cancer Treatment?
The level of TS expression in tumor tissues can be a predictive biomarker for the efficacy of TS-targeting drugs. Patients with low TS expression tend to respond better to fluoropyrimidine-based therapies. Conversely, high TS expression is often linked to poor response and worse clinical outcomes. Therefore, assessing TS levels can help in personalizing cancer treatment and selecting the most effective therapeutic strategies.
