What Are the Current Advances in Telomerase-Based Therapies?
Several telomerase-based therapies are currently under investigation:
GRN163L (Imetelstat): A lipid-conjugated oligonucleotide that directly inhibits telomerase activity by binding to the RNA template component, TERC. hTERT Vaccines: Vaccines that elicit an immune response against cells expressing the TERT protein. Gene Editing: Techniques like CRISPR/Cas9 are being explored to disrupt the TERT gene specifically in cancer cells.
